Percutaneous epiphysiodesis: experimental study and preliminary clinical results. 1986

S T Canale, and T A Russell, and R L Holcomb

An experimental study was conducted to determine the feasibility of using percutaneous drilling and pneumatic burring under image intensification to effect premature closure of the distal femoral epiphyseal plate in immature New Zealand white rabbits. Serial roentgenograms were made before the animals were killed at 6 or 10 weeks to document leg length inequality as compared with the contralateral leg following the procedure. Microscopic examination of nonoperated and operated epiphyseal plate revealed complete arrest of the operated epiphysis with bone fusion at the epiphyseal plate in eight of the nine rabbits. Since this animal study, 13 children have undergone percutaneous epiphysiodesis. Roentgenographically, all the growth plates appeared fused following the procedure. However, complete growth arrest cannot be substantiated until skeletal maturity. This is a preliminary report of a procedure that needs further documentation.

UI MeSH Term Description Entries
D007870 Leg Length Inequality A condition in which one of a pair of legs fails to grow as long as the other, which could result from injury or surgery. Inequalities, Leg Length,Inequality, Leg Length,Leg Length Inequalities,Length Inequalities, Leg,Length Inequality, Leg
D008297 Male Males
D010027 Osteotomy The surgical cutting of a bone. (Dorland, 28th ed) Osteotomies
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D005269 Femur The longest and largest bone of the skeleton, it is situated between the hip and the knee. Trochanter,Greater Trochanter,Lesser Trochanter,Femurs,Greater Trochanters,Lesser Trochanters,Trochanter, Greater,Trochanter, Lesser,Trochanters,Trochanters, Greater,Trochanters, Lesser
D006132 Growth Plate The area between the EPIPHYSIS and the DIAPHYSIS within which bone growth occurs. Cartilage, Epiphyseal,Epiphyseal Cartilage,Epiphyseal Plate,Cartilages, Epiphyseal,Epiphyseal Cartilages,Epiphyseal Plates,Growth Plates,Plate, Epiphyseal,Plate, Growth,Plates, Epiphyseal,Plates, Growth
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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