-transparent.png){kind=logo}
Thirty seven Chinese adults and 23 children in Hong Kong with myasthenia gravis were tested for HLA-A and -B antigens and acetylcholine receptor (AChR) antibody. HLA BW46 had a significantly increased prevalence in patients with juvenile onset ocular myasthenia gravis. Only one third of the juvenile ocular patients had AChR antibodies and the titres were generally low. In the adult patients taken as a whole there was a non-significant increase in the prevalence of HLA B5 and HLA B15. HLA BW46 was more prevalent in adult patients without AChR antibody and less prevalent in patients with AChR antibody but the findings were not statistically significant. It is suggested that ocular myasthenia gravis is determined by a pathological mechanism for which susceptibility is determined by HLA BW46. There was a strong correlation between ocular myasthenia gravis and Graves' disease in the adult patients. The possibility that ocular myasthenia gravis is accentuated by a BW46-associated predisposition to ocular Graves' disease is considered.
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
January 1978,
Transactions of the American Neurological Association,
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
June 1992,
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry,
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
January 1983,
British medical journal (Clinical research ed.),
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
April 1983,
British medical journal (Clinical research ed.),
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
February 1982,
Archives of neurology,
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
May 1984,
Journal of neurology, neurosurgery, and psychiatry,
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
July 1992,
Acta neurologica Scandinavica,
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
November 1989,
Acta neurologica Scandinavica,
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
December 2015,
Journal of neuroimmunology,
B R Hawkins, and
M S Ip, and
K S Lam, and
J T Ma, and
C L Wy, and
R T Yeung, and
R L Dawkins
October 1983,
The Medical journal of Australia,
