-transparent.png){kind=logo}
The renal clearances of [14C]glycocholate, [14C]taurocholate and [3H]glycochenodeoxycholate-3-sulphate were determined in bile duct obstructed rats. Comparisons of the bile acid clearances with glomerular filtration rates (GFR) indicate that most of the filtered bile acids are reabsorbed. Inhibition studies with p-aminohippurate (PAH) and probenecid suggest that a proportion of the bile acids in urine is secreted. Attempts were made to increase the renal clearance of the bile acids by the administration of pharmacological agents. An infusion of sodium acetate (0.3 mol/l) increased the clearance of the radioactive bile acids and augmented the urinary excretion of endogenous 3 alpha-hydroxy bile acids and reduced their concentration in plasma.
A Chitranukroh, and
G Taggart, and
B H Billing
July 1984,
Clinical science (London, England : 1979),
A Chitranukroh, and
G Taggart, and
B H Billing
January 2003,
Journal of gastroenterology,
A Chitranukroh, and
G Taggart, and
B H Billing
October 1991,
Hepatology (Baltimore, Md.),
A Chitranukroh, and
G Taggart, and
B H Billing
September 1975,
Clinica chimica acta; international journal of clinical chemistry,
A Chitranukroh, and
G Taggart, and
B H Billing
October 2003,
The Journal of surgical research,
A Chitranukroh, and
G Taggart, and
B H Billing
October 1975,
Acta hepato-gastroenterologica,
A Chitranukroh, and
G Taggart, and
B H Billing
February 1985,
Clinical science (London, England : 1979),
A Chitranukroh, and
G Taggart, and
B H Billing
January 1978,
Investigative radiology,
A Chitranukroh, and
G Taggart, and
B H Billing
November 1947,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
A Chitranukroh, and
G Taggart, and
B H Billing
November 1998,
Gut,
