Acro-osteolysis associated with hypertrophic pulmonary osteoarthropathy and pachydermoperiostosis. 1985

B Joseph, and V Chacko

The authors report two cases of marked acro-osteolysis. One patient, a 16-year-old boy, had hypertrophic pulmonary osteoarthropathy associated with bronchiectasis, clubbing of the digits, synovitis, and osseous changes. The other patient, a 55-year-old man, had pachydermoperiostosis as well as synovial hypertrophy, clubbing of the digits, blepharitis, and a cataract. While the association of acro-osteolysis and pachydermoperiostosis has been reported before, this appears to be the first verified case of acro-osteolysis combined with hypertrophic pulmonary osteoarthropathy.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010004 Osteoarthropathy, Primary Hypertrophic A condition chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, SEBORRHEA; HYPERHIDROSIS; periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. Inheritance is primarily autosomal recessive, but an autosomal dominant form exists. Pachydermoperiostosis,Acropachy, Hereditary,Clubbing of Digits,Cranioosteoarthropathy,Currarino Idiopathic Osteoarthropathy,Digital Clubbing, Isolated Congenital,Familial Idiopathic Osteoarthropathy Of Childhood,Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant,Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive,Idiopathic Hypertrophic Osteoarthropathy,Pachydermoperiostosis, Autosomal Dominant,Pachydermoperiostosis, Autosomal Recessive,Primary Hypertrophic Osteoarthropathy, Autosomal Dominant,Touraine-Solente-Gole Syndrome,Acropachies, Hereditary,Autosomal Dominant Pachydermoperiostoses,Autosomal Dominant Pachydermoperiostosis,Autosomal Recessive Pachydermoperiostosis,Cranioosteoarthropathies,Hereditary Acropachies,Hereditary Acropachy,Hypertrophic Osteoarthropathy, Idiopathic,Hypertrophic Osteoarthropathy, Primary,Osteoarthropathy, Currarino Idiopathic,Osteoarthropathy, Idiopathic Hypertrophic,Pachydermoperiostoses, Autosomal Dominant,Primary Hypertrophic Osteoarthropathy,Recessive Pachydermoperiostosis, Autosomal,Touraine Solente Gole Syndrome
D010005 Osteoarthropathy, Secondary Hypertrophic Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed) Clubbed Fingers,Marie-Bamberger Disease,Hypertrophic Osteoarthropathy, Secondary,Secondary Hypertrophic Osteoarthropathy,Clubbed Finger,Disease, Marie-Bamberger,Finger, Clubbed,Fingers, Clubbed,Hypertrophic Osteoarthropathies, Secondary,Marie Bamberger Disease,Osteoarthropathies, Secondary Hypertrophic,Secondary Hypertrophic Osteoarthropathies
D010014 Osteolysis Dissolution of bone that particularly involves the removal or loss of calcium. Osteolyses
D011859 Radiography Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film). Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D001862 Bone Resorption Bone loss due to osteoclastic activity. Bone Loss, Osteoclastic,Osteoclastic Bone Loss,Bone Losses, Osteoclastic,Bone Resorptions,Loss, Osteoclastic Bone,Losses, Osteoclastic Bone,Osteoclastic Bone Losses,Resorption, Bone,Resorptions, Bone
D005385 Fingers Four or five slender jointed digits in humans and primates, attached to each HAND. Finger
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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