Biomaterial Database

The closed cryosurgical treatment of giant cell tumor. 1985

P A Jacobs, and R E Clemency

Twelve patients with giant cell tumor (GCT) treated by the closed method of cryotherapy along with curettage and bone grafting were reviewed retrospectively. Follow-up examinations ranged from two years and two months to 11 years. There was one osseous and one soft-tissue recurrence. There were no thermally related soft-tissue complications. Five patients suffered six postoperative pathologic fractures. Joint function was well preserved in ten of 12 patients, although five patients have varying degrees of joint pain or instability. Closed cryotherapy, curettage, and bone grafting are effective in the treatment of GCT. Special attention to surgical approach, controlled freezing, bone grafting technique, and a supervised rehabilitation program will minimize the incidence of postoperative pathologic fracture and maximize joint function.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011884	Radius	The outer shorter of the two bones of the FOREARM, lying parallel to the ULNA and partially revolving around it.	Radial Tuberosity,Radial Tuberosities,Tuberosities, Radial,Tuberosity, Radial
D001859	Bone Neoplasms	Tumors or cancer located in bone tissue or specific BONES.	Bone Cancer,Cancer of Bone,Cancer of the Bone,Neoplasms, Bone,Bone Neoplasm,Neoplasm, Bone
D003452	Cryosurgery	The use of freezing as a special surgical technique to destroy or excise tissue.	Cryoablation,Cryoablations,Cryosurgeries
D005260	Female		Females
D005264	Femoral Fractures	Fractures of the femur.	Femoral Fracture,Fracture, Femoral,Fractures, Femoral
D005266	Femoral Neoplasms	New abnormal growth of tissue in the FEMUR.	Femoral Neoplasm,Neoplasm, Femoral,Neoplasms, Femoral
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D005598	Fractures, Spontaneous	Fractures occurring as a result of disease of a bone or from some undiscoverable cause, and not due to trauma. (Dorland, 27th ed)	Fractures, Pathological,Fracture, Pathologic,Fracture, Pathological,Fractures, Pathologic,Pathological Fracture,Pathological Fractures,Fracture, Spontaneous,Pathologic Fracture,Pathologic Fractures,Spontaneous Fracture,Spontaneous Fractures
D005870	Giant Cell Tumors	Tumors of bone tissue or synovial or other soft tissue characterized by the presence of giant cells. The most common are giant cell tumor of tendon sheath and GIANT CELL TUMOR OF BONE.	Cell Tumor, Giant,Cell Tumors, Giant,Giant Cell Tumor,Tumor, Giant Cell,Tumors, Giant Cell