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Coxiella burnetii established a persistent infection of various cell lines including L929 mouse fibroblasts. Although the basis for such persistence is unknown, the phenomenon does require continual growth, proliferation, and maintenance of viability of the host cells. We examined the effect of short- and long-term infection on the host cell's generation time and cell cycle. Flow cytometric studies of actively growing normal and infected cells stained with mithramycin or propidium iodide revealed no significant difference in cell cycle distribution patterns or changes in ploidy level associated with persistent infection with either phase I or phase II C. burnetii. The population doubling times of infected and normal cells were similar.
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
May 1989,
Antimicrobial agents and chemotherapy,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
June 1983,
Infection and immunity,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
October 1993,
Infection and immunity,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
July 1987,
Infection and immunity,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
January 1982,
Bio Systems,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
January 2015,
Veterinaria italiana,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
October 1966,
Journal of immunology (Baltimore, Md. : 1950),
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
October 2007,
Medicina clinica,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
October 2020,
Infection and immunity,
O G Baca, and
T O Scott, and
E T Akporiaye, and
R DeBlassie, and
H A Crissman
January 2014,
Protein and peptide letters,
