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Structural identification of the purine ring-opened form of N-(deoxyguanosin-8-yl)-4-aminoquinoline 1-oxide. 1985

B Bailleul, and S Galiègue-Zouitina, and B Perly, and M H Loucheux-Lefebvre

Alkaline pH treatment of N-(deoxyguanosin-8-yl)-4-amino-quinoline 1-oxide forms two quinoline derivatives. The two compounds were analyzed together by mass and 500 MHz 1H-n.m.r. spectroscopies and were identified as two 7,8-guanine ring-opened rotamers: 1-(1'-deoxyriboside)-1-[6-(2,5-diamino-4-oxo-pyrimidinyl)]-3-(4-quino linyl 1-oxide) urea.

UI MeSH Term Description Entries
D009682 Magnetic Resonance Spectroscopy Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING). In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D003849 Deoxyguanosine A nucleoside consisting of the base guanine and the sugar deoxyribose.
D006868 Hydrolysis The process of cleaving a chemical compound by the addition of a molecule of water.
D000634 Aminoquinolines Quinolines substituted in any position by one or more amino groups.
D013058 Mass Spectrometry An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers. Mass Spectroscopy,Spectrometry, Mass,Spectroscopy, Mass,Spectrum Analysis, Mass,Analysis, Mass Spectrum,Mass Spectrum Analysis,Analyses, Mass Spectrum,Mass Spectrum Analyses,Spectrum Analyses, Mass

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