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A mutant cell line of porcine kidney cells that resists the cytopathic effect of influenza virus has been obtained and characterized. These cells, designated ESK-R, were originally obtained by prolonged cultivation of cells surviving influenza B/Kanagawa/73 virus infection. No infectious virus was recovered from ESK-R cells, and no evidence for the presence of virus antigens in the cells was demonstrated by immunofluorescent staining. ESK-R cells also showed a distinct resistance to various other strains of both types A and B influenza viruses. The growth of mumps, Sendai, or Newcastle disease virus was considerably restricted, but the cell line normally supported the replication of vesicular stomatitis virus. ESK-R cells were found to lack specific receptors for influenza virus as determined by fluorescence-activated cell sorter analyses. The membrane barrier of ESK-R cells was successfully overcome by nonspecific endocytosis of calcium-coprecipitated virus particles followed by production of an appreciable amount of progeny virus.
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
January 1982,
Microbiology and immunology,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
September 2012,
The Journal of general virology,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
October 2001,
Journal of virology,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
November 2021,
Japanese journal of infectious diseases,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
January 2003,
In vitro cellular & developmental biology. Animal,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
November 2019,
Poultry science,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
July 2010,
Journal of clinical microbiology,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
January 1976,
The Indian journal of medical research,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
December 1981,
The Journal of cell biology,
Y Kimura, and
T Yokochi, and
T Miyadai, and
K Yoshida, and
J Yokoo, and
K Matsumoto
January 2013,
Virus research,
