-transparent.png){kind=logo}
Generation of an induced pluripotent stem cell line from a Kennedy Disease patient with AR mutation. 2025
Emergency and Critical Care Department, University of Health and Rehabilitation Sciences (Qingdao Central Hospital), Qingdao 266042, China.
A human induced pluripotent stem cell (iPSC) line was generated from patient with Kennedy Disease (KD), who carried the CAG repeat expansion mutation in AR gene. Peripheral blood mononuclear cells (PBMCs) were reprogrammed using non-integrating delivery of KFL4, OCT4, SOX2, BCL-XL and c-MYC. The iPSC line expresses pluripotency markers, displays a normal karyotype, and is capable of differentiate into three germ layers in vitro. This iPSC line represents a valuable cell model for studing KD in humans.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
February 2025,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
December 2021,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
July 2022,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
May 2020,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
December 2024,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
August 2020,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
May 2020,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
March 2025,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
April 2024,
Stem cell research,
Meng Zhang, and
Rui Liu, and
Pengpeng Sun, and
Chengsen Zhang, and
Jingdong Wang, and
Changjiang Li
December 2024,
Stem cell research,
