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A major aim of this study was to determine the diagnostic value of 4 electrophysiological tests in MS, and particularly their effectiveness in detecting signs of brainstem involvement. Therefore, auditory brainstem evoked response (ABER), somatosensory evoked response (SSER), blink reflex and electronystagmographic (ENG) investigative methods were applied to a group of 89 patients with definite, probable or possible multiple sclerosis (MS). The 4 methods yielded interdependent data, especially where the brainstem function was concerned, thus it can be concluded that a single demyelinating lesion may cause a combination of electrophysiological disorders within a small structure such as the brainstem. ENG recordings were found to reveal the highest number of asymptomatic abnormalities. The combination of ABER and ENG tests revealed electrophysiological disorders in 81% of all patients. The blink reflex and the SSER tests gave hardly supplementary information.
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
May 2014,
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques,
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
March 2013,
Expert review of neurotherapeutics,
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
January 1973,
Acta neurologica Scandinavica,
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
June 2009,
Multiple sclerosis (Houndmills, Basingstoke, England),
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
April 2002,
Annals of the New York Academy of Sciences,
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
January 1965,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
September 1982,
Journal of neurology, neurosurgery, and psychiatry,
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
May 2000,
Journal of neurovirology,
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
January 1977,
Clinical and experimental neurology,
E A Sanders, and
J P Reulen, and
L A Hogenhuis, and
E A van der Velde
December 1997,
Clinical autonomic research : official journal of the Clinical Autonomic Research Society,
