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The presence of significant concentrations of carnitine in red blood cells is documented using an assay procedure that is described in detail. Red blood cells can be prepared for assay by simple techniques and stored frozen. The reproducibility of the assay procedure is within acceptable limits. Usefulness of the procedure in an experimental setting has been documented with an investigation of both plasma and red blood cell carnitine concentrations of rats of different ages. Earlier studies have demonstrated that plasma carnitine concentrations are two-fold higher in adult male rats than in adult female rats. In agreement with that data, the adult male rat has a red blood cell carnitine concentration which is two-fold higher than that of adult female rats.
P R Borum, and
C M York, and
S G Bennett
March 1988,
Biochimica et biophysica acta,
P R Borum, and
C M York, and
S G Bennett
January 1991,
Acta paediatrica Hungarica,
P R Borum, and
C M York, and
S G Bennett
April 2004,
Mediators of inflammation,
P R Borum, and
C M York, and
S G Bennett
February 1990,
Biochimica et biophysica acta,
P R Borum, and
C M York, and
S G Bennett
September 1987,
The American journal of clinical nutrition,
P R Borum, and
C M York, and
S G Bennett
January 1994,
European neurology,
P R Borum, and
C M York, and
S G Bennett
January 2000,
Renal failure,
P R Borum, and
C M York, and
S G Bennett
October 1994,
Infusionstherapie und Transfusionsmedizin,
P R Borum, and
C M York, and
S G Bennett
September 1966,
The Journal of general physiology,
P R Borum, and
C M York, and
S G Bennett
March 1990,
The American journal of clinical nutrition,
