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Anti-idiotypic antibodies to four monoclonal IgM, one polyclonal IgM, and one polyclonal IgA rheumatoid factors were produced in rabbits and tested for cross reactivity with rheumatoid factors from nine patients with essential mixed cryoglobulinaemia, three patients with rheumatoid arthritis, four patients with systemic sicca syndrome, and one patient with systemic lupus erythematosus. Variable (3/16 to 10/16) cross reactivity for each anti-idiotypic antibody was observed which was not restricted by disease category, clonality, or isotype of the rheumatoid factor. These findings suggest that rheumatoid factor genes are highly conserved from the germ-line antibody repertoire.
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
January 1991,
Autoimmunity,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
January 1985,
Concepts in immunopathology,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
April 1988,
Annals of the rheumatic diseases,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
January 1991,
Clinical and experimental rheumatology,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
March 1988,
Immunology letters,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
January 1988,
Springer seminars in immunopathology,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
January 1994,
Materia medica Polona. Polish journal of medicine and pharmacy,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
January 1976,
Scandinavian journal of rheumatology,
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
July 1986,
Journal of immunology (Baltimore, Md. : 1950),
A E Gharavi, and
B M Patel, and
G R Hughes, and
K B Elkon
November 1989,
Anales de medicina interna (Madrid, Spain : 1984),
