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A radiolabelled monoclonal antibody (NDOG2) directed against placental alkaline phosphatase (PLAP) was used in the radio-immunodetection of ovarian carcinoma. Tumour deposits were successfully visualized in 11 of 15 patients and the abnormalities demonstrated were classified as focal or diffuse. Of the 11 patients, eight showed focal abnormalities alone and three had a diffuse abnormality, of which two also showed a focal abnormality. False-positive results may occur not only due to uptake of 123I by gut mucosa and an inadequately blocked thyroid gland but also from activity in an incompletely emptied bladder. A false-negative result occurred due to high background activity in the liver masking a known, discrete tumour deposit.
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
March 1986,
Clinical radiology,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
December 1983,
Nihon Sanka Fujinka Gakkai zasshi,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
January 2009,
Pathology international,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
January 1990,
The Journal of nuclear medicine and allied sciences,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
May 1985,
British journal of cancer,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
January 1989,
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
January 2005,
Human antibodies,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
February 1986,
The British journal of radiology,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
September 1986,
Nihon Sanka Fujinka Gakkai zasshi,
J O Davies, and
E R Davies, and
K Howe, and
P C Jackson, and
E M Pitcher, and
C S Sadowski, and
G M Stirrat, and
C A Sunderland
May 1997,
The Journal of urology,
