-transparent.png){kind=logo}
A morphometric analysis of the corpus striatum of rats chronically treated with haloperidol was performed at the light and electron microscopic levels. Although the density of striatal neurons was unchanged in the haloperidol-treated group, there was a small increase in neuronal size (13%). This change in cell size was paralleled by a trend towards larger dendrite calibres occurring in the drug-treated animals. The distribution curve for axon terminal size indicated that 12% of the overall population was shifted from a range with a median size of 0.8 micron 2 to one with 1.6 micron 2 in the drug-treated group. This increase in size of some striatal terminals was accompanied by a concomitant increase in numbers of their associated synaptic vesicles, resulting in a similar density of vesicles for both control and drug-treated animals.
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
December 1992,
Clinical neuropharmacology,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
May 1992,
The Journal of pharmacology and experimental therapeutics,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
March 2008,
Neuropharmacology,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
April 2001,
European journal of pharmacology,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
July 2008,
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
January 1984,
Biomedica biochimica acta,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
April 1975,
Brain research,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
August 1997,
Experimental neurology,
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
April 1991,
Synapse (New York, N.Y.),
F M Benes, and
P A Paskevich, and
J Davidson, and
V B Domesick
December 2003,
Neuroreport,
