Inter-laboratory study on the separation of cinchona alkaloids by high-performance liquid chromatography.
1985
M A Johnston, and
A R Lea, and
D M Hailey
UI
MeSH Term
Description
Entries
D011802
Quinidine
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.