The relationship between pedal asymmetries and handedness has been the subject of several investigations. Support for pedal asymmetries occurring in the normal population have been reported which are claimed to be a function of handedness and sex. If true, these asymmetries would confound the assessment of trophic changes due to localized brain injury. However, at least four attempts to replicate these results have failed. The present study was undertaken to reassess this hypothesis using more rigorous measurement of handedness and foot length with a more representative sample allowing for larger hand by sex groups than has been previously used. No differences in the direction of foot size were found regardless of hand or sex classification.