Chronic lymphocytic leukemia presenting as an anal mass. 1985

D H Cresson, and G P Siegal

A middle-aged man sought medical attention because of a large perianal mass. The lesion was caused by a massive subepithelial infiltrate of small neoplastic lymphocytes representing a localized tissue manifestation of chronic lymphocytic leukemia. This report emphasizes the possibility of leukemia/lymphomas occurring at the anus, to stress that leukemia should be considered in the differential diagnosis of patients presenting with perianal disease in the presence of lymphadenopathy and constitutional symptoms.

UI MeSH Term Description Entries
D007945 Leukemia, Lymphoid Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts. Leukemia, Lymphocytic,Lymphocytic Leukemia,Lymphoid Leukemia,Leukemias, Lymphocytic,Leukemias, Lymphoid,Lymphocytic Leukemias,Lymphoid Leukemias
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D004848 Epithelium The layers of EPITHELIAL CELLS which cover the inner and outer surfaces of the cutaneous, mucus, and serous tissues and glands of the body. Mesothelium,Epithelial Tissue,Mesothelial Tissue,Epithelial Tissues,Mesothelial Tissues,Tissue, Epithelial,Tissue, Mesothelial,Tissues, Epithelial,Tissues, Mesothelial
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001003 Anal Canal The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus. Anal Gland, Human,Anal Sphincter,Anus,Anal Gland,Anal Glands, Human,Detrusor External Sphincter,External Anal Sphincter,Internal Anal Sphincter,Anal Sphincter, External,Anal Sphincter, Internal,Anal Sphincters,Detrusor External Sphincters,External Anal Sphincters,Human Anal Gland,Human Anal Glands,Internal Anal Sphincters,Sphincter, Anal,Sphincter, Detrusor External,Sphincter, External Anal,Sphincter, Internal Anal,Sphincters, Anal
D001005 Anus Neoplasms Tumors or cancer of the ANAL CANAL. Anal Cancer,Cancer of Anus,Anal Neoplasms,Cancer of the Anus,Neoplasms, Anal,Neoplasms, Anus,Anal Cancers,Anal Neoplasm,Anus Cancer,Anus Cancers,Anus Neoplasm,Cancer, Anal,Cancers, Anal,Neoplasm, Anal,Neoplasm, Anus
D001706 Biopsy Removal and pathologic examination of specimens from the living body. Biopsies

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