| D001777 |
Blood Coagulation |
The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot. |
Blood Clotting,Coagulation, Blood,Blood Clottings,Clotting, Blood |
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| D005337 |
Fibrin |
A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot. |
Antithrombin I |
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| D005340 |
Fibrinogen |
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. |
Coagulation Factor I,Factor I,Blood Coagulation Factor I,gamma-Fibrinogen,Factor I, Coagulation,gamma Fibrinogen |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D000721 |
Ancrod |
An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-. |
Agkistrodon Serine Proteinase,Agkistrodon rhodostoma Venom Protease,Arvin,Arvin IRC-50,Arwin,Venacil,Arvin IRC 50,Arvin IRC50 |
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| D013917 |
Thrombin |
An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN. |
Thrombase,Thrombin JMI,Thrombin-JMI,Thrombinar,Thrombostat,alpha-Thrombin,beta,gamma-Thrombin,beta-Thrombin,gamma-Thrombin,JMI, Thrombin |
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| D046911 |
Macromolecular Substances |
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure. |
Macromolecular Complexes,Macromolecular Compounds,Macromolecular Compounds and Complexes,Complexes, Macromolecular,Compounds, Macromolecular,Substances, Macromolecular |
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