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Cytosol receptors for estrogens (ER) and progestins (PR) were assayed in human prostatic carcinoma (CaP) and benign prostatic hyperplasia (BPH). Specimens were obtained from either the peripheral or the periurethral zone of the prostate. Stringent criteria were used to identify and measure 7-8S specific receptor using sucrose gradient analysis in a vertical tube rotor. Progesterone receptor was found in 14 BPH samples assayed and in 12 of 13 prostate cancers. In contrast, the 7-8S estrogen receptor was found in none of the nine benign samples assayed and in all prostate cancers. BPH samples were taken from either peripheral or periurethral zones and gave similar results. The histology of individual specimens did not correlate with either the ER or PR present, and, in the cancers, there was no correlation between the pathologic stage or the Gleason score and receptor content.
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
January 1984,
Clinical neuropharmacology,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
January 1992,
Neuroepidemiology,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
March 1978,
Investigative urology,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
March 1982,
Journal of steroid biochemistry,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
September 1984,
Diseases of the colon and rectum,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
January 1987,
Hormone research,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
May 1987,
Cancer research,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
November 1982,
Cancer,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
June 1988,
Obstetrics and gynecology,
R M Wolf, and
S L Schneider, and
J E Pontes, and
L Englander, and
J P Karr, and
G P Murphy, and
A A Sandberg
January 1991,
Annals of the New York Academy of Sciences,
