Biomaterial Database

Epidemiological study of Enterobacter cloacae resistant to 3rd generation cephalosporins: a preliminary report. 1985

H Giamarellou, and G Koratzanis, and K Kanellakopoulou, and G K Daikos

In 1983 an increase in the resistance rate of cefotaxime against Enterobacter cloacae strains was observed in "Laikos General" hospital, that reached 59.3% in the 2nd half of the same year. All strains resistant to cefotaxime were found resistant to cefamandole, moxalactam and ceftriaxone while 61.8% were also resistant to amikacin. Urine represented the main source of isolation, particularly from the catheterized patient of the Renal Transplantation Unit in whom cefuroxime was mostly over used. Multiresistant strains were virulent since 5 patients died of septicemia. Mechanisms of resistance to cefotaxime are speculated upon because resistance work-up has not yet been completed. SHV, was exclusively isolated in the limited number of strains which have been studied up to now.

UI	MeSH Term	Description	Entries
D002511	Cephalosporins	A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.	Antibiotics, Cephalosporin,Cephalosporanic Acid,Cephalosporin,Cephalosporin Antibiotic,Cephalosporanic Acids,Acid, Cephalosporanic,Acids, Cephalosporanic,Antibiotic, Cephalosporin,Cephalosporin Antibiotics
D004352	Drug Resistance, Microbial	The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).	Antibiotic Resistance,Antibiotic Resistance, Microbial,Antimicrobial Resistance, Drug,Antimicrobial Drug Resistance,Antimicrobial Drug Resistances,Antimicrobial Resistances, Drug,Drug Antimicrobial Resistance,Drug Antimicrobial Resistances,Drug Resistances, Microbial,Resistance, Antibiotic,Resistance, Drug Antimicrobial,Resistances, Drug Antimicrobial
D004754	Enterobacter	Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.
D004755	Enterobacteriaceae	A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.	Coliform Bacilli,Enterobacteria,Ewingella,Leclercia,Paracolobactrum,Sodalis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man