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By neurophysiologic investigations, we evaluated 20 patients with olivopontocerebellar atrophy (OPCA), comprising 8 with glutamate dehydrogenase (GDH) deficiency and 12 with normal GDH activity. We found sensorimotor, predominantly sensory axonal neuropathy distally in the legs, and peripheral auditory nerve dysfunction (prolonged wave I but normal interpeak latencies in brainstem auditory evoked response) in GDH-deficient patients. These findings seem distinctive enough to serve as the electrophysiologic marker for diagnosis and monitoring of treatment and progression of the disease. The pattern-reversal visual and median nerve somatosensory evoked responses did not differ among the patients and controls.
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
July 1986,
Journal of the neurological sciences,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
January 1987,
Neurology,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
March 1986,
Annals of neurology,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
February 1986,
Italian journal of neurological sciences,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
May 1989,
Archives of disease in childhood,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
March 1987,
Electromyography and clinical neurophysiology,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
January 1988,
Yonsei medical journal,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
January 2001,
Ryoikibetsu shokogun shirizu,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
January 1977,
Neurologia i neurochirurgia polska,
S Chokroverty, and
R C Duvoisin, and
R Sachdeo, and
J Sage, and
F Lepore, and
W Nicklas
December 1995,
Annals of neurology,
