Auditory-evoked potential correlates of susceptibility to noise-induced hearing loss. 1985

J Attias, and H Pratt

Correlations between changes in cochlear microphonics (CM) and auditory brainstem-evoked potentials (ABEP) resulting from transitory-threshold-shift (TTS)-inducing noise, in normally hearing subjects, and the eventual permanent threshold shift (PTS) which the same subjects developed after 9-14 months of well-quantified occupational noise were evaluated. In addition, the predictive value of pigmentation, as an indicator of eventual PTS, was assessed. Eleven CM and ABEP indices which showed significant correlation with the eventual hearing loss were identified. Eight of these indices reflect the effect of increased stimulus rate and experimental TTS-inducing noise. These results show that the difference in ABEP latencies as a result of increased stimulus rate is smaller in persons with large eventual PTS (high susceptibility to noise-induced hearing loss). The effect is larger in persons that eventually developed a small PTS (low susceptibility). Pigmentation, as reflected by iris and skin color, was found to have a negative correlation with susceptibility to noise, i.e. the more pigment the less PTS developed. The above indices may be useful to determine personal susceptibility to noise in normally hearing subjects.

UI MeSH Term Description Entries
D009623 Noise, Occupational Noise present in occupational, industrial, and factory situations. Occupational Noise,Noises, Occupational,Occupational Noises
D010858 Pigmentation Coloration or discoloration of a part by a pigment. Pigmentations
D003055 Cochlear Microphonic Potentials The electric response of the cochlear hair cells to acoustic stimulation. Cochlear Microphonic Potential,Potential, Cochlear Microphonic,Potentials, Cochlear Microphonic
D004198 Disease Susceptibility A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases. Diathesis,Susceptibility, Disease,Diatheses,Disease Susceptibilities,Susceptibilities, Disease
D006317 Hearing Loss, Noise-Induced Hearing loss due to exposure to explosive loud noise or chronic exposure to sound level greater than 85 dB. The hearing loss is often in the frequency range 4000-6000 hertz. Acoustic Trauma,Hearing Loss, Noise Induced,Noise-Induced Hearing Loss
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001299 Audiometry The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds. Audiometries
D001300 Audiometry, Evoked Response A form of electrophysiologic audiometry in which an analog computer is included in the circuit to average out ongoing or spontaneous brain wave activity. A characteristic pattern of response to a sound stimulus may then become evident. Evoked response audiometry is known also as electric response audiometry. Audiometry, Electroencephalic Response,Electrocochleography,Evoked Response Audiometry,Audiometries, Electroencephalic Response,Audiometries, Evoked Response,Electrocochleographies,Electroencephalic Response Audiometries,Electroencephalic Response Audiometry,Evoked Response Audiometries,Response Audiometries, Electroencephalic,Response Audiometries, Evoked,Response Audiometry, Electroencephalic,Response Audiometry, Evoked

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