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Differential-gain ECG (DG-ECG) recordings were made to investigate the mechanism of tachyarrhythmias. The study comprised experimental and clinical series. Experimental findings demonstrated two types (local and circulatory) of vulnerability manifested during induced tachyarrhythmia. Differential-gain ECG recordings were used in the clinical series to specify experimentally-demonstrated mechanisms of tachyarrhythmias: differentiate focal and circulatory excitation sources and specify the localization of both the sources of tachycardia and additional atrioventricular bundles associated with the ventricular pre-excitation syndrome.
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