-transparent.png){kind=logo}
In vivo 31-P nuclear magnetic resonance (NMR) spectroscopy was performed on cat brains injected with hematoporphyrin derivative (HpD). A 2-cm-diam region of the right parietal lobe was photoactivated with red light. The 31-P NMR spectra of the photoactivated hemisphere revealed increased inorganic phosphate and decreased phosphocreatine and adenosine triphosphate (ATP) levels, compared to spectra obtained from the control hemisphere. In the absence of drug, no difference in spectra was observed between the photoradiated and control lobes. Our studies suggest that in vivo 31-P NMR spectroscopy may be used to monitor the effects of phototherapy on tissue high-energy phosphate metabolism.
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
January 1985,
Magnetic resonance imaging,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
January 1989,
In vivo (Athens, Greece),
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
January 1983,
Pharmacology, biochemistry, and behavior,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
April 1989,
Science in China. Series B, Chemistry, life sciences & earth sciences,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
January 1997,
European psychiatry : the journal of the Association of European Psychiatrists,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
December 1986,
Cancer research,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
January 1981,
Tumori,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
August 2000,
Magnetic resonance in medicine,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
July 1986,
The Journal of surgical research,
M Chopp, and
J A Helpern, and
S Frinak, and
F W Hetzel, and
J R Ewing, and
K M Welch
January 1984,
Progress in clinical and biological research,
