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In ovariectomized rats treated with estradiol benzoate the ICV introduction of PGE1, 11-deoxy-13,14-didehydro-16S-methyl-PGE2, PGI2 or 6 H-PGI1 produces a marked increase of the plasma prolactin levels. These results suggest that the PGs play a role in the regulation of the prolactin secretion.
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