-transparent.png){kind=logo}
The synthesis of two series of amides and glycinamides starting from N-phenyl exo-5,6-trimethylenenorbornan-2-endo-amine, prepared from exo-5,6-trimethylenenorbornan-2-one via sodium borohydride reduction of its N-phenyl imine, is described. All amides showed a moderate hypotensive activity in rats, whereas some glycinamides and amides showed weak infiltration anesthesia and antiarrhythmic activity in mice. Effects on heart rate in rats are also reported.
Related Publications
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
June 1971,
Bollettino chimico farmaceutico,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
July 2004,
Bioorganic & medicinal chemistry letters,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
May 1969,
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
May 1988,
Journal of medicinal chemistry,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
October 2011,
Molecules (Basel, Switzerland),
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
March 2024,
RSC advances,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
June 1965,
Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
November 1963,
Journal of medicinal chemistry,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
November 1986,
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
M Longobardi, and
P Schenone, and
A Bargagna, and
C Matera, and
F Rossi, and
E Marmo
January 2002,
Bollettino chimico farmaceutico,
