Thymectomy in multiple sclerosis: a 3-year follow-up. 1985

J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson

We studied 34 MS patients who were treated experimentally by thymectomy with or without 1 year of azathioprine therapy. After 3 years, there was no evidence of benefit. Relapsing-remitting patients had done as well or better clinically than controls, and the chronic progressive group did less well statistically than controls.

UI MeSH Term Description Entries
D009103 Multiple Sclerosis An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) MS (Multiple Sclerosis),Multiple Sclerosis, Acute Fulminating,Sclerosis, Disseminated,Disseminated Sclerosis,Sclerosis, Multiple
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013934 Thymectomy Surgical removal of the thymus gland. (Dorland, 28th ed) Thymectomies

Related Publications

J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
May 1998, European journal of neurology,
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
March 2021, Diagnostics (Basel, Switzerland),
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
February 1997, Brain : a journal of neurology,
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
January 2004, Neuroepidemiology,
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
September 2018, Multiple sclerosis (Houndmills, Basingstoke, England),
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
August 1999, Multiple sclerosis (Houndmills, Basingstoke, England),
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
November 2010, Acta neurologica Scandinavica,
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
June 2001, Journal of the neurological sciences,
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
February 1996, Italian journal of neurological sciences,
J L Trotter, and D B Clifford, and E B Montgomery, and T B Ferguson
March 2017, Acta neurologica Belgica,
Copied contents to your clipboard!