The possible mechanisms of the disturbed circadian sleep-wake rhythm after time zone changes. 1985

S Endo, and M Sasaki

Changes in sleep after eastward flight; To go to bed at 2300 hr in SFO, which corresponds to 1600 hr in TYO, means that a traveller from TYO starts his sleep from evening nap in TYO. In evening naps, Slow Wave Sleep(SWS) is increased and REM sleep is decreased. In the flight from West to East, however, the subjects experienced one night total sleep deprivation. Consequently, it is necessary to do research on naps after total sleep deprivation. REM sleep is clearly increased in the morning and decreased in the evening in spite of one night total sleep deprivation. These findings indicate that the distribution of REM sleep is not affected by total sleep deprivation, but REM sleep has a clear circadian rhythm. By contrast, SWS is increased in the morning, afternoon and evening naps after total sleep deprivation. Thus, SWS is more independent of circadian effects and responsive to the length of prior wakefulness. From the findings mentioned above, it is assumed that the decrease of REM sleep and the increase of SWS in the first part of the sleep in SFO may be caused by effects of one night total sleep deprivation and circadian rhythm of REM sleep. Changes in sleep after westward flight; The sleep after returning home from east and after the flight from TYO to LDN was different from that in baseline nights in TYO, with decreased REM sleep latency, appearance of SOREMs and increased REM sleep. Since the sleep after westward flight corresponds to that in the early morning to forenoon in the place before the flight, it is necessary to investigate the effect of sleep reversal and naps in daytime. In naps after one night total sleep deprivation, morning naps had shortened REM sleep latency, increased REM sleep and frequent SOREMs. From the findings mentioned above, it is suggested that the nocturnal sleep after returning home from east and in LDN may reflect the circadian rhythm of sleep in the place before the start of the flight.

UI MeSH Term Description Entries
D008297 Male Males
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D002940 Circadian Rhythm The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs or environmental and physiological stimuli. Diurnal Rhythm,Nyctohemeral Rhythm,Twenty-Four Hour Rhythm,Nycthemeral Rhythm,Circadian Rhythms,Diurnal Rhythms,Nycthemeral Rhythms,Nyctohemeral Rhythms,Rhythm, Circadian,Rhythm, Diurnal,Rhythm, Nycthemeral,Rhythm, Nyctohemeral,Rhythm, Twenty-Four Hour,Rhythms, Circadian,Rhythms, Diurnal,Rhythms, Nycthemeral,Rhythms, Nyctohemeral,Rhythms, Twenty-Four Hour,Twenty Four Hour Rhythm,Twenty-Four Hour Rhythms
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000337 Aerospace Medicine That branch of medicine dealing with the studies and effects of flight through the atmosphere or in space upon the human body and with the prevention or cure of physiological or psychological malfunctions arising from these effects. (from NASA Thesaurus) Aviation Medicine,Space Medicine,Medicine, Aerospace,Medicine, Aviation,Medicine, Space
D012892 Sleep Deprivation The state of being deprived of sleep under experimental conditions, due to life events, or from a wide variety of pathophysiologic causes such as medication effect, chronic illness, psychiatric illness, or sleep disorder. Inadequate Sleep,Insufficient Sleep,Insufficient Sleep Syndrome,REM Sleep Deprivation,Sleep Debt,Sleep Fragmentation,Sleep Insufficiency,Deprivation, REM Sleep,Deprivation, Sleep,Fragmentation, Sleep,Insufficiencies, Sleep,Insufficiency, Sleep,Insufficient Sleep Syndromes,Sleep Deprivation, REM,Sleep Insufficiencies,Sleep, Inadequate,Sleep, Insufficient,Syndrome, Insufficient Sleep
D012894 Sleep Stages Periods of sleep manifested by changes in EEG activity and certain behavioral correlates; they formerly included Stage 1: sleep onset, drowsy sleep; Stage 2: light sleep; Stages 3 and 4: delta sleep, light sleep, deep sleep, telencephalic sleep. In 2007, sleep stages were redefined by The American Academy of Sleep Medicine (AASM) as: N1-N2 (sleep onset - light sleep), N3 (SLOW-WAVE SLEEP), and REM SLEEP. N1-Sleep,N2-Sleep,NREM Stage 1,NREM Stage 2,N1 Sleep,N2 Sleep,Sleep Stage,Stage, Sleep,Stages, Sleep
D012895 Sleep, REM A stage of sleep characterized by rapid movements of the eye and low voltage fast pattern EEG. It is usually associated with dreaming. Fast-Wave Sleep,Paradoxical Sleep,Rapid Eye Movements,Rhombencephalic Sleep,Sleep, Fast-Wave,REM Sleep,Eye Movement, Rapid,Eye Movements, Rapid,Fast Wave Sleep,Movement, Rapid Eye,Movements, Rapid Eye,Rapid Eye Movement,Sleep, Fast Wave,Sleep, Paradoxical,Sleep, Rhombencephalic
D013026 Space Flight Travel beyond the earth's atmosphere. Space Exploration,Space Travel,Spaceflight,Exploration, Space,Explorations, Space,Flight, Space,Flights, Space,Space Explorations,Space Flights,Space Travels,Spaceflights,Travel, Space,Travels, Space

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