Percutaneous penetration of hair dyes. 1985

L J Wolfram, and H I Maibach

Scalp penetration of 7 hair dyes (oxidative and direct) that occurs under conditions of hair dye usage was evaluated for both rhesus monkey and man using 14C labeled materials by quantifying their absorbtion via urine assays. Both species showed a remarkably similar pattern of dye penetration. The extent of scalp penetration is slightly higher for direct dyes but in neither case does it exceed 1% of the applied dose.

UI MeSH Term Description Entries
D008253 Macaca mulatta A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans. Chinese Rhesus Macaques,Macaca mulatta lasiota,Monkey, Rhesus,Rhesus Monkey,Rhesus Macaque,Chinese Rhesus Macaque,Macaca mulatta lasiotas,Macaque, Rhesus,Rhesus Macaque, Chinese,Rhesus Macaques,Rhesus Macaques, Chinese,Rhesus Monkeys
D006202 Hair Dyes Dyes used as cosmetics to change hair color either permanently or temporarily. Coloring Agents, Hair,Dyes, Hair,Hair Colorants,Hair Dye,Agents, Hair Coloring,Colorants, Hair,Dye, Hair,Hair Coloring Agents
D006203 Hair Preparations Hair grooming, cleansing and modifying products meant for topical application to hair, usually human. They include sprays, bleaches, dyes, conditioners, rinses, shampoos, nutrient lotions, etc. Cosmetics, Hair,Hair Cosmetic,Hair Preparation,Cosmetic, Hair,Hair Cosmetics,Preparation, Hair,Preparations, Hair
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012535 Scalp The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL). Scalps
D012869 Skin Absorption Uptake of substances through the SKIN. Absorption, Skin,Intracutaneous Absorption,Intradermal Absorption,Percutaneous Absorption,Transcutaneous Absorption,Transdermal Absorption,Absorption, Intracutaneous,Absorption, Intradermal,Absorption, Percutaneous,Absorption, Transcutaneous,Absorption, Transdermal,Absorptions, Intracutaneous,Absorptions, Intradermal,Absorptions, Percutaneous,Absorptions, Skin,Absorptions, Transcutaneous,Absorptions, Transdermal,Intracutaneous Absorptions,Intradermal Absorptions,Percutaneous Absorptions,Skin Absorptions,Transcutaneous Absorptions,Transdermal Absorptions

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