Lead and cadmium in breast milk. Higher levels in urban vs rural mothers during the first 3 months of lactation. 1985

H J Sternowsky, and R Wessolowski

Breast milk from 10 women each from the city of Hamburg and from a rural area was analyzed by atomic absorption spectrometry for contamination with lead and cadmium. Samples were examined at regular intervals for 3 months after birth. On day 5 a diurnal profile was analyzed; on the other days milk was taken before and after the morning feed. Daily permissible intake (DPI) for lead is 5 micrograms/kg/day for children; the DPI for cadmium has as yet been determined only for adults as 400-500 micrograms/week, equivalent to about 1 microgram/kg/day (WHO 1972). For breast milk as the main source of nutrition in infants, this study shows values of 9.1 +/- 2.5 (SD) microgram/l for lead in the rural population, with a tendency to decrease towards the end of lactation. Urban mothers had 13.3 +/- 5.5 (SD) microgram/l, with a tendency to increase. This difference was significant only on day 45. Mean cadmium content in rural mothers was 17.3 +/- 4.9 micrograms/l, with much higher values in the colostrum and a decrease after 15 days. Urban mothers had 24.6 +/- 7.3 micrograms/l, again with high colostrum values and a subsequent decrease. These latter values are not significantly different. Calculated daily intake according to these values is presented, based on 840 ml breast milk for a 5.5 kg infant per day. Rural infants ingested 0.9-1.3 micrograms/kg/day of lead, and in the city 1.5-2.3 micrograms/kg/day. Cadmium intake in rural infants amounted from 1.2-1.8 micrograms/kg/day; in Hamburg it was 1.6-2.2 micrograms/kg/day.(ABSTRACT TRUNCATED AT 250 WORDS)

UI MeSH Term Description Entries
D007774 Lactation The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN. Lactation, Prolonged,Milk Secretion,Lactations, Prolonged,Milk Secretions,Prolonged Lactation,Prolonged Lactations
D007854 Lead A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.
D008895 Milk, Human Milk that is produced by HUMAN MAMMARY GLANDS. Breast Milk,Human Milk,Milk, Breast
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D002104 Cadmium An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012424 Rural Population The inhabitants of rural areas or of small towns classified as rural. Rural Residence,Rural Communities,Rural Spatial Distribution,Communities, Rural,Community, Rural,Distribution, Rural Spatial,Distributions, Rural Spatial,Population, Rural,Populations, Rural,Residence, Rural,Rural Community,Rural Populations,Rural Residences,Rural Spatial Distributions
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014505 Urban Population The inhabitants of a city or town, including metropolitan areas and suburban areas. Urban Residence,Urban Spatial Distribution,Distribution, Urban Spatial,Distributions, Urban Spatial,Population, Urban,Populations, Urban,Residence, Urban,Urban Populations,Urban Residences,Urban Spatial Distributions

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