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Protein-thiol groups that react with dihydroxydinaphthyl disulphide during a 7 h incubation (so-called reactive protein thiols, PSHr) have been quantitatively measured on sections of human uterine cervix by microcytospectrophotometry. Measurements were made on areas (1 micron 2) of epithelium and adjoining stroma in samples of normal cervix, and in samples obtained from patients with dysplasia, carcinoma-in-situ and invasive cancer. The ratio of PSHr in epithelium to stroma is substantially reduced in the pathological conditions compared with normal and in apparently normal adjacent areas. Such changes in PSHr are discussed in relation to the redox balance of the tissue, and free radical disturbances previously described.
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F Bajardi, and
C Benedetto, and
G Bussolati, and
S Cianfano, and
M U Dianzani, and
B Ghiringhello, and
G Nöhammer, and
W Rojanapo, and
E Schauenstein
August 2006,
Archives of pathology & laboratory medicine,
T F Slater, and
F Bajardi, and
C Benedetto, and
G Bussolati, and
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M U Dianzani, and
B Ghiringhello, and
G Nöhammer, and
W Rojanapo, and
E Schauenstein
January 1986,
Ultrastructural pathology,
T F Slater, and
F Bajardi, and
C Benedetto, and
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G Nöhammer, and
W Rojanapo, and
E Schauenstein
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Cancer,
T F Slater, and
F Bajardi, and
C Benedetto, and
G Bussolati, and
S Cianfano, and
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B Ghiringhello, and
G Nöhammer, and
W Rojanapo, and
E Schauenstein
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British journal of cancer,
T F Slater, and
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C Benedetto, and
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E Schauenstein
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Annals of diagnostic pathology,
T F Slater, and
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C Benedetto, and
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G Nöhammer, and
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E Schauenstein
January 1984,
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T F Slater, and
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C Benedetto, and
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G Nöhammer, and
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E Schauenstein
October 2008,
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico,
T F Slater, and
F Bajardi, and
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B Ghiringhello, and
G Nöhammer, and
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E Schauenstein
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International journal of gynecological cancer : official journal of the International Gynecological Cancer Society,
T F Slater, and
F Bajardi, and
C Benedetto, and
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M U Dianzani, and
B Ghiringhello, and
G Nöhammer, and
W Rojanapo, and
E Schauenstein
February 1995,
Nihon Sanka Fujinka Gakkai zasshi,
T F Slater, and
F Bajardi, and
C Benedetto, and
G Bussolati, and
S Cianfano, and
M U Dianzani, and
B Ghiringhello, and
G Nöhammer, and
W Rojanapo, and
E Schauenstein
July 1996,
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