-transparent.png){kind=logo}
In our wide experience of treating advanced breast carcinoma with chemotherapy, the combination of doxorubicin (DOX), vincristine (VCR), cyclophosphamide (CPM) and fluorouracil (FU) gave a complete plus partial response rate of over 60%, with 100% alopecia and frequent cardiac toxicity depending on total dose. After the EORTC Clinical Screening Group phase II trial we have conducted an "expected difference method" comparative phase II trial using the combination DOX, VCR, CPM, FU and the combination of MTX (10mg/m2), VCR, CPM and FU on a population of 50 breast carcinoma patients similar to those taking part in the first study. The reasons for similarity of action will be presented and discussed.
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
October 1988,
Chemioterapia : international journal of the Mediterranean Society of Chemotherapy,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
January 1989,
Oncology,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
April 1975,
Cancer,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
February 2005,
Onkologie,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
September 1984,
Seminars in oncology,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
June 1987,
Cancer,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
May 1997,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
January 1996,
Breast cancer research and treatment,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
October 1984,
Cancer treatment reports,
R Metz, and
M Delgado, and
R Keiling, and
P Cappelaere, and
J P Armand, and
G Prevot, and
J L Misset, and
J Grimbert, and
G Mathe
January 1990,
British journal of cancer,
