Biomaterial Database

Thin-layer chromatographic screening procedure for undeclared synthetic drugs in Chinese herbal preparations. 1985

S Yuen, and C A Lau-Cam

A simple and rapid thin-layer chromatographic procedure was developed for the detection and presumptive identification of seventeen synthetic drugs previously reported as adulterants of Chinese herbal preparations. Depending on its complexity, the sample may be directly extracted into aqueous ethanol, or stepwise fractionated into acidic, basic, and neutral components. Extracts are analyzed on silica gel layers containing a fluorescent indicator with the aid of two solvent systems. Spots are visualized under short and long wavelength ultraviolet lights. The procedure was successfully tested on synthetic and commercial samples.

UI	MeSH Term	Description	Entries
D007202	Indicators and Reagents	Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)	Indicator,Reagent,Reagents,Indicators,Reagents and Indicators
D008516	Medicine, Chinese Traditional	A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.	Chinese Medicine, Traditional,Chung I Hsueh,Traditional Medicine, Chinese,Zhong Yi Xue,Chinese Traditional Medicine,Traditional Chinese Medicine,Traditional Tongue Assessment,Traditional Tongue Diagnosis,Hsueh, Chung I,Tongue Assessment, Traditional,Tongue Diagnoses, Traditional,Tongue Diagnosis, Traditional,Traditional Tongue Assessments,Traditional Tongue Diagnoses
D010946	Plants, Medicinal	Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.	Herbs, Medicinal,Medicinal Herbs,Healing Plants,Medicinal Plants,Pharmaceutical Plants,Healing Plant,Herb, Medicinal,Medicinal Herb,Medicinal Plant,Pharmaceutical Plant,Plant, Healing,Plant, Medicinal,Plant, Pharmaceutical,Plants, Healing,Plants, Pharmaceutical
D002855	Chromatography, Thin Layer	Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Chromatography, Thin-Layer,Thin Layer Chromatography,Chromatographies, Thin Layer,Chromatographies, Thin-Layer,Thin Layer Chromatographies,Thin-Layer Chromatographies,Thin-Layer Chromatography
D004340	Drug Contamination	The presence of organisms, or any foreign material that makes a drug preparation impure.	Drug Adulteration,Drug Contamination, Chemical,Drug Contamination, Microbial,Drug Contamination, Physical,Drug Impurity,Adulteration, Drug,Chemical Drug Contamination,Chemical Drug Contaminations,Contamination, Chemical Drug,Contamination, Drug,Contamination, Microbial Drug,Contamination, Physical Drug,Contaminations, Chemical Drug,Contaminations, Microbial Drug,Contaminations, Physical Drug,Drug Adulterations,Drug Contaminations,Drug Contaminations, Chemical,Drug Contaminations, Microbial,Drug Contaminations, Physical,Drug Impurities,Impurity, Drug,Microbial Drug Contamination,Microbial Drug Contaminations,Physical Drug Contamination,Physical Drug Contaminations

Related Publications

S Yuen, and C A Lau-Cam

Thin-layer chromatographic screening procedure for some drugs in horse plasma.

November 1989, Journal of chromatography,

S Yuen, and C A Lau-Cam

Quantitative thin layer chromatographic multi-sulfonamide screening procedure.

July 1983, Journal - Association of Official Analytical Chemists,

S Yuen, and C A Lau-Cam

A thin-layer chromatographic screening procedure for detecting drug abuse.

November 1968, Technical bulletin of the Registry of Medical Technologists. American Society of Clinical Pathologists. Registry of Medical Technologists,

S Yuen, and C A Lau-Cam

A simple, rapid thin-layer chromatographic drug screening procedure.

July 1974, Journal of chromatography,

S Yuen, and C A Lau-Cam

Rapid quantitative thin layer chromatographic screening procedure for sulfathiazole residues in honey.

January 1986, Journal - Association of Official Analytical Chemists,

S Yuen, and C A Lau-Cam

Quantitative thin layer chromatographic multi-sulfonamide screening procedure: collaborative study.

July 1983, Journal - Association of Official Analytical Chemists,

S Yuen, and C A Lau-Cam

Thin-layer chromatographic screening procedure for some drugs used in treatment of arthritis: "arthritic cures" prescribed in Mexico.

July 1977, Journal of chromatography,