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Serum creatine kinase (CK) activity was measured after intramuscular injections in 44 patients hospitalized for non-cardiac reasons. The drugs injected were: diazepam, dipyrone, metoclopramide, meperidine, pentazocine and procaine penicillin. Only 3 out of 44 patients (7%) demonstrated significant elevation of CK levels following the intramuscular injections. In these 3 patients the elevation was mainly due to a rise of the MM-isoenzyme fraction with MB levels increased in one patient. These findings do not justify the common clinical notion of regarding intramuscular injections as a frequent cause of serum CK elevation. It is concluded that high CK serum values in a patient with chest pain should always be considered with utmost suspicion, disregarding the possible effects of a previous intramuscular injection.
F Konikoff, and
J Halevy, and
E Theodor
June 1973,
Schweizerische medizinische Wochenschrift,
F Konikoff, and
J Halevy, and
E Theodor
July 1973,
JAMA,
F Konikoff, and
J Halevy, and
E Theodor
November 1997,
Medicina clinica,
F Konikoff, and
J Halevy, and
E Theodor
May 1975,
The Medical journal of Australia,
F Konikoff, and
J Halevy, and
E Theodor
January 1970,
The American journal of the medical sciences,
F Konikoff, and
J Halevy, and
E Theodor
February 1971,
The Medical annals of the District of Columbia,
F Konikoff, and
J Halevy, and
E Theodor
January 1977,
Vutreshni bolesti,
F Konikoff, and
J Halevy, and
E Theodor
March 1994,
Annals of clinical biochemistry,
F Konikoff, and
J Halevy, and
E Theodor
May 1973,
Cardiovascular research,
F Konikoff, and
J Halevy, and
E Theodor
February 1988,
Klinische Wochenschrift,
