C3 and C6 complement types in schizophrenia. 1985

C Rudduck, and L Beckman, and G Franzén, and L Lindström

C3 and C6 complement types were studied in schizophrenic patients and controls. The distributions of the three common C3 types (F, FS and S) among the patients was significantly different from that in the controls (p less than 0.005) and the frequency of the C3F gene was significantly increased (p less than 0.0005) among the patients. There were no significant differences in C6 gene or phenotype frequencies between patient and controls.

UI MeSH Term Description Entries
D003176 Complement C3 A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase. C3 Complement,C3 Precursor,Complement 3,Complement C3 Precursor,Complement Component 3,Precursor-Complement 3,Pro-C3,Pro-Complement 3,C3 Precursor, Complement,C3, Complement,Complement, C3,Component 3, Complement,Precursor Complement 3,Precursor, C3,Precursor, Complement C3,Pro C3,Pro Complement 3
D003183 Complement C6 A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6. C6 Complement,Complement 6,Complement Component 6,C6, Complement,Complement, C6,Component 6, Complement
D005787 Gene Frequency The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION. Allele Frequency,Genetic Equilibrium,Equilibrium, Genetic,Allele Frequencies,Frequencies, Allele,Frequencies, Gene,Frequency, Allele,Frequency, Gene,Gene Frequencies
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012559 Schizophrenia A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. Dementia Praecox,Schizophrenic Disorders,Disorder, Schizophrenic,Disorders, Schizophrenic,Schizophrenias,Schizophrenic Disorder

Related Publications

C Rudduck, and L Beckman, and G Franzén, and L Lindström
January 1992, Human heredity,
C Rudduck, and L Beckman, and G Franzén, and L Lindström
April 1988, Gene geography : a computerized bulletin on human gene frequencies,
C Rudduck, and L Beckman, and G Franzén, and L Lindström
January 1985, Human heredity,
C Rudduck, and L Beckman, and G Franzén, and L Lindström
January 2019, Chemistry (Weinheim an der Bergstrasse, Germany),
C Rudduck, and L Beckman, and G Franzén, and L Lindström
January 1985, Human heredity,
C Rudduck, and L Beckman, and G Franzén, and L Lindström
March 1986, Human genetics,
C Rudduck, and L Beckman, and G Franzén, and L Lindström
January 1985, Human heredity,
C Rudduck, and L Beckman, and G Franzén, and L Lindström
January 1993, Human heredity,
C Rudduck, and L Beckman, and G Franzén, and L Lindström
November 2019, Molecules (Basel, Switzerland),
C Rudduck, and L Beckman, and G Franzén, and L Lindström
January 1990, Human heredity,
Copied contents to your clipboard!