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In cultured chick embryo chondrocytes, type X collagen is preferentially deposited in the extracellular matrix, the ratio between type II and type X collagen being about 5 times higher in the culture medium than in the cell layer. When the newly synthesized collagens deposited in slices from the epiphyseal cartilage of 17-day-old embryo tibiae were isolated, type X collagen was always the major species. In agreement with this result the mRNA for type X collagen was the predominant mRNA species purified from the same tissue. When the total collagen (unlabeled) deposited in the epiphyseal cartilage was analyzed, it was observed that type X collagen represented only 1/15 of the type II collagen recovered in the same preparation. The possible explanations for these differences are discussed.
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
January 1990,
Annals of the New York Academy of Sciences,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
August 2018,
Biomaterials,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
May 1986,
The Journal of cell biology,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
April 2003,
Matrix biology : journal of the International Society for Matrix Biology,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
June 2016,
Osteoarthritis and cartilage,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
January 1993,
Connective tissue research,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
February 1996,
Experimental cell research,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
December 2009,
Arthritis and rheumatism,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
November 2002,
Cell and tissue research,
R Cancedda, and
O Capasso, and
P Castagnola, and
F Descalzi-Cancedda, and
N Quarto
October 1990,
Proceedings of the National Academy of Sciences of the United States of America,
