-transparent.png){kind=logo}
79 patients with primary generalized epilepsies have been treated with DPA in a medium dosage of 51 mg/kg bodyweight/day, range 14 to 125 mg/kg/day, for a medium time of 22 months, range 2 to 49 months. 51 children out of this group had been treated previously and were therapy resistant to other medications. 27 children got DPA for their first medication. 34 patients were treated with DPA as a single drug, 45 were treated in combination with other medications. Therapeutic success was found to be remarkable good in impulsive petit mal (n = 4, all patients without any more seizures), in absences (n = 52, complete success in 84%), and in primary generalized grand mal seizures with spike-waves in the EEG alone or in combination with petit mal (n = 30, 87% success). However, centrencephalic myoclonic-astatic seizures (n = 17, no more seizures in 35%) were influenced significantly less. Side effects were rarely seen, mostly they could be observed in those patients treated with DPA and another medication. Side effects never induced interruption of treatment with DPA.
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
November 2000,
Current treatment options in neurology,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
June 1973,
Munchener medizinische Wochenschrift (1950),
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
May 1973,
Fortschritte der Medizin,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
January 2003,
Epilepsia,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
January 1988,
Seminars in neurology,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
January 1987,
Epilepsia,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
January 1981,
Acta neuropathologica. Supplementum,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
November 1997,
Journal of child neurology,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
January 1977,
Rivista di neurologia,
I Lagenstein, and
E Blaschke-Zimmermann, and
E Iffland, and
H J Sternowsky, and
R Fehr
March 2024,
Revue neurologique,
