[The variability of plasma protein binding of phenytoin in epileptic patients with hypoalbuminemia]. 1985

K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010672 Phenytoin An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs. Diphenylhydantoin,Fenitoin,Phenhydan,5,5-Diphenylhydantoin,5,5-diphenylimidazolidine-2,4-dione,Antisacer,Difenin,Dihydan,Dilantin,Epamin,Epanutin,Hydantol,Phenytoin Sodium,Sodium Diphenylhydantoinate,Diphenylhydantoinate, Sodium
D011485 Protein Binding The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. Plasma Protein Binding Capacity,Binding, Protein
D001798 Blood Proteins Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins. Blood Protein,Plasma Protein,Plasma Proteins,Serum Protein,Serum Proteins,Protein, Blood,Protein, Plasma,Protein, Serum,Proteins, Blood,Proteins, Plasma,Proteins, Serum
D004827 Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) Aura,Awakening Epilepsy,Seizure Disorder,Epilepsy, Cryptogenic,Auras,Cryptogenic Epilepsies,Cryptogenic Epilepsy,Epilepsies,Epilepsies, Cryptogenic,Epilepsy, Awakening,Seizure Disorders
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
August 1983, Archives of neurology,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
August 1982, British journal of clinical pharmacology,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
April 1984, Archives of neurology,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
January 2013, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
August 1970, Journal of neurology, neurosurgery, and psychiatry,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
January 1988, Therapeutic drug monitoring,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
April 1980, The Journal of pharmacology and experimental therapeutics,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
June 2002, Therapeutic drug monitoring,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
February 1994, Chest,
K Mamada, and Y Kasuya, and J Henmi, and Y Takahashi, and K Someya, and Y Takao, and Y Sasaki
December 1979, British journal of clinical pharmacology,
Copied contents to your clipboard!