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Urinary N-acetyl-beta-D-glucosaminidase activity was examined in 41 patients who received a 5-day course of aminoglycoside. Both pretreatment N-acetyl-beta-D-glucosaminidase values and the increase in N-acetyl-beta-D-glucosaminidase after treatment were high in elderly groups, suggesting the increased vulnerability of the kidney with aging.
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