Haemoglobin D-beta-thalassaemia in a German family. A double heterozygous haemoglobinopathy. 1985

H Piechowiak, and M Krause, and E Kohne

This report concerns a young woman, whose stained blood films revealed a hypochromic and microcytic red cell morphology. It could be shown by haemoglobin analysis that this atypical blood film was due to a double heterozygote disorder of haemoglobin D (Hb D) and beta-thalassaemia. The thalassaemia trait was inherited from her father and the Hb D from her mother. This is the first observation of this rare disorder in a German family. Comparable cases reported in the literature are mentioned.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010375 Pedigree The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition. Family Tree,Genealogical Tree,Genealogic Tree,Genetic Identity,Identity, Genetic,Family Trees,Genealogic Trees,Genealogical Trees,Genetic Identities,Identities, Genetic,Tree, Family,Tree, Genealogic,Tree, Genealogical,Trees, Family,Trees, Genealogic,Trees, Genealogical
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D005860 Germany, West The former Federal Republic of Germany which was reunified with the former German Democratic Republic in 1990. Federal Republic of Germany,Germany, Federal Republic of
D006455 Hemoglobins, Abnormal Hemoglobins characterized by structural alterations within the molecule. The alteration can be either absence, addition or substitution of one or more amino acids in the globin part of the molecule at selected positions in the polypeptide chains. Abnormal Hemoglobins
D006579 Heterozygote An individual having different alleles at one or more loci regarding a specific character. Carriers, Genetic,Genetic Carriers,Carrier, Genetic,Genetic Carrier,Heterozygotes
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

H Piechowiak, and M Krause, and E Kohne
August 1984, The Indian journal of medical research,
H Piechowiak, and M Krause, and E Kohne
January 1975, Acta haematologica,
H Piechowiak, and M Krause, and E Kohne
July 1968, Journal of clinical pathology,
H Piechowiak, and M Krause, and E Kohne
June 1965, British medical journal,
H Piechowiak, and M Krause, and E Kohne
January 1979, Acta medica Austriaca,
H Piechowiak, and M Krause, and E Kohne
March 1969, British journal of haematology,
H Piechowiak, and M Krause, and E Kohne
January 1999, European journal of human genetics : EJHG,
H Piechowiak, and M Krause, and E Kohne
November 1968, Nature,
Copied contents to your clipboard!