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Altogether 47 patients with advanced laryngeal and laryngopharyngeal tumors were treated. Twenty-six patients received multimodality therapy including local UHF-hyperthermia and gamma-beam therapy; 21 patients receiving radiotherapy only were entered in the control group. Hyperthermia was induced by the electromagnetic field with the frequency of 2450 and 915 MHz. Parus and Plot units were used. External irradiation was provided. Clinically, complete primary tumor regression was achieved in 20 of 26 patients. A positive effect was absent in 3 cases when metastasis size was 10 X 12 X 8 cm. In the control group, clinically complete tumor regression was noted in 2 patients only. In 4 cases the effect was insignificant, in the rest of 15 cases various degrees of a decrease in tumor and metastasis sizes were revealed.
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