BIOMAT Database Logo BIOMAT Database Logo

[Adenine nucleotide and creatine phosphate levels in rat skeletal muscles and myocardium in myorelaxation]. 1985

O V Krapivina

The content of adenylic system components and creatine phosphate was determined in skeletal muscles and myocardium after intraperitoneal injection and short-term action of myorelaxin and arduan. The injected myorelaxin causes no significant changes in macroergic phosphates in skeletal muscles, whereas arduan lowers the ATP amount by 39%. The both myorelaxants have the same effect on the adenylic system components of the myocardium: they lower significantly the level of ATP and enhance that of ADP and AMP. Different variational tendences of variation in the content of creatine phosphate in skeletal muscles (a certain rise) and in the myocardium (a decrease more than by 30%) are observed.

UI MeSH Term Description Entries
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009206 Myocardium The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow. Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D009466 Neuromuscular Blocking Agents Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc. Neuromuscular Blocker,Neuromuscular Blocking Agent,Neuromuscular Blockers,Agent, Neuromuscular Blocking,Agents, Neuromuscular Blocking,Blocker, Neuromuscular,Blockers, Neuromuscular,Blocking Agent, Neuromuscular,Blocking Agents, Neuromuscular
D009467 Neuromuscular Depolarizing Agents Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. Depolarizing Muscle Relaxants,Muscle Relaxants, Depolarizing,Depolarizing Blockers,Agents, Neuromuscular Depolarizing,Blockers, Depolarizing,Depolarizing Agents, Neuromuscular,Relaxants, Depolarizing Muscle
D010725 Phosphocreatine An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996) Creatine Phosphate,Neoton,Phosphocreatine, Disodium Salt,Phosphorylcreatine,Disodium Salt Phosphocreatine,Phosphate, Creatine
D000227 Adenine Nucleotides Adenine Nucleotide,Adenosine Phosphate,Adenosine Phosphates,Nucleotide, Adenine,Nucleotides, Adenine,Phosphate, Adenosine,Phosphates, Adenosine
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

O V Krapivina
Rat skeletal muscle glyceraldehyde-3-phosphate dehydrogenase: adenine nucleotide-induced inactivation.
November 1976, Archives of biochemistry and biophysics,
O V Krapivina
Adenine nucleotide and creatine phosphate pool in adult and old rat heart during immobilization stress.
January 2002, Gerontology,
O V Krapivina
[Dependence of creatine kinase and glycogen synthetase activities of skeletal muscles on state of adenine nucleotide phosphorylation and cAMP metabolism].
January 1980, Ukrainskii biokhimicheskii zhurnal (1978),
O V Krapivina
[Creatine kinase distribution in the subcellular fractions of rat myocardium and skeletal muscles and some of its properties].
January 1972, Ukrains'kyi biokhimichnyi zhurnal,
O V Krapivina
Correlation between membrane potential, creatine phosphate, and lactate in rat myocardium.
February 1983, Die Pharmazie,
O V Krapivina
Quantitative histochemistry of creatine kinase in rat myocardium and skeletal muscle.
November 1988, The Histochemical journal,
O V Krapivina
[Effect of denervation on the nucleotide and creatine phosphate level in various muscles].
January 1973, Ukrains'kyi biokhimichnyi zhurnal,
O V Krapivina
[BEHAVIOR OF ADENINE NUCLEOTIDES AND CREATINE PHOSPHATE IN THE MYOCARDIUM IN FUNCTIONAL RECOVERY AFTER PROLONGED ASPHYXIA].
January 1964, Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung,
O V Krapivina
Hypothyroidism delays ischemia-induced contracture and adenine nucleotide depletion in rat myocardium.
May 1987, Circulation research,
O V Krapivina
Decreased restitution of creatine phosphate in white and red skeletal muscles during aging.
September 1968, Experientia,
Copied contents to your clipboard!