-transparent.png){kind=logo}
We studied the transport of glycylsarcosine by the brush-border membrane vesicles isolated from normal term human placentas. This dipeptide resisted hydrolysis by placental membrane vesicles and was transported intact into an osmotically responsive intravesicular space. The transport process was Na+-independent and probably occurred down a concentration gradient. Many peptides inhibited the transport of glycylsarcosine whereas amino acids had no effect. These results demonstrate, for the first time, the presence of a dipeptide transport system in the human placenta.
Related Publications
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
January 1996,
Placenta,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
June 1975,
Biochimica et biophysica acta,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
January 1996,
The Journal of experimental biology,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
June 1981,
The Journal of physiology,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
March 1978,
Pflugers Archiv : European journal of physiology,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
December 1977,
The Biochemical journal,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
May 1981,
The Journal of biological chemistry,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
March 1992,
Biochimica et biophysica acta,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
February 1996,
Biochemistry and molecular biology international,
M E Ganapathy, and
V B Mahesh, and
L D Devoe, and
F H Leibach, and
V Ganapathy
November 1990,
The Journal of pharmacology and experimental therapeutics,
