Biomaterial Database

[Primperan: recent pharmacological data on its gastromotor effect]. 1985

P Frontenas

Two types of pharmacological action explain the therapeutic effectiveness of Primperan in gastroenterology: an anti-emetic effect due to a central dopaminergic mechanism and a motor effect on the gastro-intestinal tract due to a cholinergic mechanism. Research is currently underway to explain the origin of the cholinergic potential of metoclopramide.

UI	MeSH Term	Description	Entries
D008787	Metoclopramide	A dopamine D2 antagonist that is used as an antiemetic.	4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide,Cerucal,Maxolon,Metaclopramide,Metoclopramide Dihydrochloride,Metoclopramide Hydrochloride,Metoclopramide Monohydrochloride,Metoclopramide Monohydrochloride, Monohydrate,Primperan,Reglan,Rimetin,Dihydrochloride, Metoclopramide,Hydrochloride, Metoclopramide,Monohydrochloride, Metoclopramide
D005769	Gastrointestinal Motility	The motor activity of the GASTROINTESTINAL TRACT.	Intestinal Motility,Gastrointestinal Motilities,Intestinal Motilities,Motilities, Gastrointestinal,Motilities, Intestinal,Motility, Gastrointestinal,Motility, Intestinal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014839	Vomiting	The forcible expulsion of the contents of the STOMACH through the MOUTH.	Emesis