Chronic and clinically significant conduct difficulties of mildly and moderately mentally retarded adults in a vocational setting were reduced with a multicomponent self-management package. Skills of self-monitoring, self-evaluation, self-consequation, and self-instruction were trained and practiced in vivo. Positive effects on behaviors not specifically treated also were noted for some subjects. A combined treatment withdrawal and multiple baseline design was used to assess changes. Nine-month follow-up under different work conditions revealed continued maintenance of treatment gains.