Long-term risk of menstrual disturbances after tubal sterilization. 1985

F DeStefano, and J A Perlman, and H B Peterson, and E L Diamond

We analyzed data from the Walnut Creek Contraceptive Drug Study to compare the menstrual characteristics of 719 women who had tubal sterilizations and 1083 women whose partners had undergone a vasectomy. Study participants were enrolled from 1968 to 1972 and followed up through 1976. The tubal sterilization group had slightly increased, though in most instances not statistically significant, risks of moderate to severe menstrual cramps and adverse menstrual bleeding. At follow-up intervals longer than 2 years, the tubal sterilization group had significantly increased risks of abnormal menstrual cycles and combinations of two or more adverse menstrual outcomes. Tubal sterilization was not associated with an increased risk of premenstrual symptoms. These findings suggest that the types of tubal sterilization procedures which were performed during the early 1970s possibly carry some increased risk of menstrual disturbances, particularly abnormal cycles, and that it may take more than 2 years for the increased risk to become apparent.

UI MeSH Term Description Entries
D008599 Menstruation Disturbances Variations of MENSTRUATION which may be indicative of disease. Hypomenorrhea,Menstruation Disorders,Menstruation, Retrograde,Polymenorrhea,Irregular Menses,Irregular Menstruation,Menstrual Irregularities,Menstrual Irregularity,Disorder, Menstruation,Disorders, Menstruation,Disturbance, Menstruation,Disturbances, Menstruation,Irregularity, Menstrual,Menses, Irregular,Menstruation Disorder,Menstruation Disturbance,Menstruation, Irregular,Retrograde Menstruation
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011293 Premenstrual Syndrome A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses. Premenstrual Tension,Premenstrual Syndromes,Premenstrual Tensions,Syndrome, Premenstrual,Syndromes, Premenstrual,Tension, Premenstrual,Tensions, Premenstrual
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012306 Risk The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome. Relative Risk,Relative Risks,Risk, Relative,Risks,Risks, Relative
D013246 Sterilization, Tubal Procedures that render the female sterile by interrupting the flow in the FALLOPIAN TUBE. These procedures generally are surgical, and may also use chemicals or physical means. Ligation, Tubal,Tubal Ligation,Aldridge Procedure,Chemical Tubal Occlusion,Cooke Method,Cornual Coagulation,Fimbriectomy,Irving Method,Kroener Fimbriectomy,Kroener Method,Madlener Method,Nonchemical Tubal Occlusion,Occlusion, Chemical Tubal,Occlusion, Nonchemical Tubal,Pomeroy Method,Pomeroy Sterilization,Tubal Occlusion,Tubal Occlusion, Chemical,Tubal Occlusion, Nonchemical,Tubal Rings,Uchida Method,Chemical Tubal Occlusions,Coagulations, Cornual,Cornual Coagulations,Fimbriectomies,Fimbriectomy, Kroener,Ligations, Tubal,Nonchemical Tubal Occlusions,Ring, Tubal,Rings, Tubal,Sterilization, Pomeroy,Sterilizations, Tubal,Tubal Ligations,Tubal Occlusions,Tubal Occlusions, Chemical,Tubal Occlusions, Nonchemical,Tubal Ring,Tubal Sterilization,Tubal Sterilizations

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