Metabolic role of free mycolic acids in Mycobacterium tuberculosis. 1977

K Takayama, and E L Armstrong

Small amounts of free mycolic acids and trehalose dimycolate that are rapidly formed by Mycobacterium tuberculosis H37Ra are probably derived from mycolyl acetyl trehalose and transferred to the cell wall. However, the transfer of mycolic acids from mycolyl acetyl trehalose to the cell wall still appears to be the more prominent route.

UI MeSH Term Description Entries
D009169 Mycobacterium tuberculosis A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation. Mycobacterium tuberculosis H37Rv
D009171 Mycolic Acids Long fatty acids found in the CELL WALLS of some ACTINOBACTERIA, including MYCOBACTERIUM TUBERCULOSIS. Mycolic Acid,Acid, Mycolic,Acids, Mycolic
D002473 Cell Wall The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents. Cell Walls,Wall, Cell,Walls, Cell
D003311 Cord Factors Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals. Trehalose Dimycolates,Cord Factor,Trehalose-6,6'-Dimycolate,Dimycolates, Trehalose,Factor, Cord,Factors, Cord,Trehalose 6,6' Dimycolate
D006017 Glycolipids Any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol (see GLYCERIDES), a sphingoid, a ceramide (CERAMIDES) (N-acylsphingoid) or a prenyl phosphate. (From IUPAC's webpage) Glycolipid
D014199 Trehalose

Related Publications

K Takayama, and E L Armstrong
June 2007, Current protocols in microbiology,
K Takayama, and E L Armstrong
May 2014, Chemistry and physics of lipids,
K Takayama, and E L Armstrong
June 1951, Comptes rendus hebdomadaires des seances de l'Academie des sciences,
K Takayama, and E L Armstrong
September 1970, Journal of general microbiology,
K Takayama, and E L Armstrong
February 2012, Wei sheng wu xue bao = Acta microbiologica Sinica,
K Takayama, and E L Armstrong
January 2005, Clinical microbiology reviews,
K Takayama, and E L Armstrong
April 2008, Chemistry and physics of lipids,
K Takayama, and E L Armstrong
January 1971, Doklady Akademii nauk SSSR,
K Takayama, and E L Armstrong
March 1987, European journal of biochemistry,
Copied contents to your clipboard!