-transparent.png){kind=logo}
Plasma and inflammatory fluid kininogen levels, and blood and inflammatory fluid free kinin levels were determined in rats 24 h after the injection of carrageenin into an air pouch. Plasma T-kininogen levels increased 7-fold. In the inflammatory fluid levels reached 8 micrograms/ml. Blood levels of free kinin showed a 5-fold increase. The kinins were identified on HPLC as T-kinin (Ile-Ser-bradykinin) and bradykinin, 63 and 37%, respectively. These results indicate for the first time that free T-kinin as well as bradykinin is released during an inflammatory response in rat and confirms our previous finding that T-kininogen may be a major acute-phase protein in inflammation.
A Barlas, and
K Sugio, and
L M Greenbaum
September 1989,
Japanese journal of pharmacology,
A Barlas, and
K Sugio, and
L M Greenbaum
April 1994,
Biochemical pharmacology,
A Barlas, and
K Sugio, and
L M Greenbaum
December 1986,
Biochemical pharmacology,
A Barlas, and
K Sugio, and
L M Greenbaum
March 2004,
Inflammation research : official journal of the European Histamine Research Society ... [et al.],
A Barlas, and
K Sugio, and
L M Greenbaum
July 1971,
British journal of pharmacology,
A Barlas, and
K Sugio, and
L M Greenbaum
September 1983,
Biochemical pharmacology,
A Barlas, and
K Sugio, and
L M Greenbaum
December 1981,
British journal of experimental pathology,
A Barlas, and
K Sugio, and
L M Greenbaum
November 1995,
Inflammation research : official journal of the European Histamine Research Society ... [et al.],
A Barlas, and
K Sugio, and
L M Greenbaum
September 1974,
British journal of pharmacology,
A Barlas, and
K Sugio, and
L M Greenbaum
January 1995,
Life sciences,
