Biomaterial Database

[Rh-incompatibility acidosis in newborn infants following intrauterine transfusion]. 1985

J W Siebers

Severe foetal Rh erythroblastosis is treated by intrauterine transfusion, in most cases with ACD adenine erythrocyte concentrates. In two cases where delivery took place shortly after the last intrauterine transfusion, metabolic acidosis developed post partum, which could possibly be attributed to the erythrocyte concentrates in the transfusion. Multiple pH level measurements in the ACD adenine erythrocyte concentrates revealed pH levels between 6.4 and 6.8. Erythrocyte concentrates prepared with heparin showed pH levels between 7.18 and 7.25 and should therefore be used for intrauterine transfusion in place of ACD adenine erythrocyte concentrates.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D001805	Blood Transfusion, Intrauterine	In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).	Fetal Transfusion,Intrauterine Transfusion,Blood Transfusions, Intrauterine,Fetal Transfusions,Intrauterine Blood Transfusion,Intrauterine Blood Transfusions,Intrauterine Transfusions,Transfusion, Fetal,Transfusion, Intrauterine,Transfusion, Intrauterine Blood,Transfusions, Fetal,Transfusions, Intrauterine,Transfusions, Intrauterine Blood
D004899	Erythroblastosis, Fetal	A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.	Hemolytic Disease of Newborn,Erythroblastosis Fetalis,Erythroblastoses, Fetal,Erythroblastosis Fetali,Fetal Erythroblastoses,Fetal Erythroblastosis,Fetali, Erythroblastosis,Fetalis, Erythroblastosis,Newborn Hemolytic Disease,Newborn Hemolytic Diseases
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000138	Acidosis	A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.	Metabolic Acidosis,Acidoses,Acidoses, Metabolic,Acidosis, Metabolic,Metabolic Acidoses
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D017707	Erythrocyte Transfusion	The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.	Red Blood Cell Transfusion,Red Blood Cell Transfusions,Transfusion, Red Blood Cell,Transfusions, Red Blood Cell,Erythrocyte Transfusions,Transfusion, Erythrocyte,Transfusions, Erythrocyte