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Implants of bone and tooth matrix powder were placed subcutaneously (s.c.) on intraperitoneal (i.p.) Mitex or Polyvic membranes. Implants were removed for histology after 1-24 weeks. Macrophages, fibroblasts, and vascular sinusoids infiltrated around bone and tooth matrix particles after one week. In the s.c. tooth matrix implants, a few sites of cartilage formation and ossification developed at two weeks, and by three weeks granulocytopoiesis and megakaryocytopoiesis developed adjacent to new bone; erythropoiesis was not observed. In s.c. bone matrix implants and in the i.p. artificial membranes coated with bone or tooth matrix powder, ossification or hematopoiesis was not observed. Small numbers of CFU-s, CFU-nm, BFU-e, and CFU-e appeared 10-20 days after s.c. implantation of tooth matrix; none were detected in s.c. bone matrix implants.
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
October 1971,
Oral surgery, oral medicine, and oral pathology,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
June 1984,
Nihon Shishubyo Gakkai kaishi,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
March 1996,
Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
January 2000,
Hematology (Amsterdam, Netherlands),
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
January 1973,
Transactions of the International Conference on Oral Surgery,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
January 1974,
Folia biologica,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
January 1978,
Archivum immunologiae et therapiae experimentalis,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
January 1981,
Stomatologiia,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
August 1988,
The Journal of laboratory and clinical medicine,
W H Knospe, and
S G Husseini, and
S S Adler, and
A H Reddi
December 2023,
ACS biomaterials science & engineering,
